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The Duchennepedia
The Duchennepedia is a resource created by all registered users of Action Duchenne. All submitted articles are moderated for accuracy, plain English and value of content by Action Duchenne Staff.
If you have valuable advice or information to pass onto the Duchenne community then write an article. If an article already exists then open it up and submit an edit or add new tags or resources. If you see an error then please edit the article yourself.
Action Duchene reserves the right to deny any entry that we deem to be inaccurate or offensive.
Action Duchenne cannot accept responsibility for the content of links to other websites.
It is essential that you always consult your Neuromuscular Consultant, GP or other health and educational professionals before taking medicines or changing interventions.
We hope that you enjoy our new encyclopedia of Duchenne information and resources. Let's not all have to reinvent the wheel - please get posting articles!
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Latest Articles
Exon Skipping Explained
- 14 Sep 2011
- Last edit by actionduchenne
- Permanent link
This article by Annemeike Rus is a brilliant explanation of exon skipping.
Tags: exon skipping.
Physical Therapy
- 27 May 2011
- Last edit by emiolu2
- Permanent link
Physical therapy can help prevent deformities, improve movement, and keep muscles as flexible an...
Tags: Physical therapy, flexibility, exercises.
Update on the Therapeutic approaches to muscular dystrophy
- 10 May 2011
- Last edit by Andreina
- Permanent link
This is a summary of the article written by Aurelie Goyenvalle, Jane T Seto, Kay E Davies and Je...
Tags: exon skipping, gene therapy, Viral Vector, Dystrophin, rAAV, Antisense Oligonucleotide, PMO, PPMO, Duchenne, muscular dystrophy, Utrophin.
£2.5m research grant for Duchenne Muscular Dystrophy awarded to Oxford researchers
- 15 Apr 2011
- Last edit by Andreina
- Permanent link
Funding for pioneering research into gene therapy by Action Duchenne has led to further funds fo...
Tags: exon skipping, Duchenne, Duchenne muscular dystrophy, Dr Matthew Wood, Mike Gait, antisense oligonucleotides.
GSK2402968 Clinical Development Programme Update
- 15 Apr 2011
- Last edit by Andreina
- Permanent link
Forty-Eight Week Follow-Up Data from a Phase I/IIa Extension Study of PRO051/GSK2402968 in Subje...
Tags: Duchenne, DMD, GSK, Duchenne Muscular Dystrophy.
AAV-mediated gene therapy to the isolated limb in rhesus macaques.
- 18 Mar 2011
- Last edit by emiolu2
- Permanent link
Center for Gene Therapy, The Research Institute at Nationwide Children’s Hospital and Depa...
Tags: gene therapy, limb, muscle, adenoassociated viral AAV.
Peptide-based inhibition of NF-?B rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.
- 11 Mar 2011
- Last edit by emiolu2
- Permanent link
Deterioration of diaphragm function is one of the prominent factors that contributes to the susc...
Tags: This article has no tags.
Co-administration of ibuprofen and nitric oxide is an effective experimental therapy for muscular dystrophy, with immediate applicability to humans
- 11 Mar 2011
- Last edit by emiolu2
- Permanent link
Background and purpose: Current therapies for muscular dystrophy are based on corticosteroids. S...
Tags: nitric oxide, inflammation, muscular dystrophy, skeletal muscle regeneration, diet, therapy.
Peptide-based inhibition of NF-?B rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.
- 11 Mar 2011
- Last edit by emiolu2
- Permanent link
Deterioration of diaphragm function is one of the prominent factors that contributes to the susc...
The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy.
- 11 Mar 2011
- Last edit by emiolu2
- Permanent link
Duchenne muscular dystrophy (DMD) is associated with mutations in the dystrophin gene that disru...
Tags: Exon Skipping, adenoassociated virus AAV, mRNA, dystrophin gene.
