making muscle wasting history

Adeno-associated virus for the treatment of musle diseases: Toward Clinical trials.

• Last Edited: 24 Jan 2011
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Muscle diseases include musclular dystrophies, cardiomyopathies, neuromuscular and metabolic disorders. The loss of muscular structure and function is associated with significant morbidity and mor...

Tags: Adenoassociated virus AAV, exon skipping.

The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy.

• Last Edited: 11 Mar 2011
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Duchenne muscular dystrophy (DMD) is associated with mutations in the dystrophin gene that disrupt the open reading frame whereas the milder Becker’s form is associated with mutations which ...

Tags: Exon Skipping, adenoassociated virus AAV, mRNA, dystrophin gene.