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Articles tagged with antisense oligonucleotides

Exon Skipping large animal

16th March 2009 Researchers from Children’s National Medical Center and colleagues in Tokyo publish results, video of first successful trial in dogs with Duchenne muscular dystrophy. WASHING...

Tags: exon skipping, dogs, antisense oligonucleotides, molecular patches, morpholinos.

Gene therapy research demonstrates promising treatment of DMD for the future

By Matthew WoodMB ChB Cape Town, MA DPhil OxfUniversity of OxfordThe latest announcement of the 150k raised by Action Duchenne to fund the latest research into ‘Exon skipping’, a gene t...

Tags: Exon Skipping, antisense oligonucleotides, peptide nucleic acids, PNA.

2-'O-methyl antisense oligos (PS) targeting exon 44.

BackgroundAntisense-mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs), the disrupted DMD reading frame is restored, allo...

Tags: antisense oligonucleotides, Duchenne muscular dystrophy, exon skipping, 28242Omethyl phosphorothioate, phosphorodiamidate morpholino oligomer.

2.5m research grant for Duchenne Muscular Dystrophy awarded to Oxford researchers

Funding for pioneering research into gene therapy by Action Duchenne has led to further funds for research into this life limiting disease A recent 2.5 million award made by the Health Innovation...

Tags: exon skipping, Duchenne, Duchenne muscular dystrophy, Dr Matthew Wood, Mike Gait, antisense oligonucleotides.