making muscle wasting history

Global excitement about potential treatments for Duchenne

• Last Edited: 18 Nov 2009
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Dr. Matthew Wood reports on recent developments in exon skipping trials from the Oligonucleotide Therapeutic Society meeting held in Fukuoka, Japan in November. Last week I attended the Oligonucle...

Tags: exon skipping, AVI.

Global excitement about potential treatments for Duchenne (Version in French)

• Last Edited: 12 Jan 2010
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Dr. Matthew Wood rapports sur les développements récents dans l’exon skipping essais de la réunion d’oligonucléotides thérapeutiques Société a lieu à Fukuoka, au Japon en Novembre. La ...

Tags: exon skipping, AVI, french.

Systemic administration of avi-4658, a Phosphorodiamiate morpholino oligomer(pmo) to induce exon 51 skipping, is well tolerated and restores dystrophin expression in duchenne muscular dystrophin (dmd) boys in a dose dependent manner

• Last Edited: 22 Nov 2010
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1) UCL institute of child health, neorology, London,UK2) Royal Victor Infirmary,Newcastle3) 3avi biopharma Bothell USAObjective : we previsiously showed that a single im dose of avi-4658 pmo skips...

Tags: exon skipping, AVI, muscle biopsy, T cells, Phosphorodiamiate morpholino oligomerpmo.