making muscle wasting history

Idebenone

• Last Edited: 15 Jul 2009
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The absence of dystrophin does not only weaken the cell membranes but also negatively affects the mitochondria in the muscle cells of Duchenne patients. In these “power stations” of the ...

Tags: Idebenone, Friedreichs ataxia, cardiomyopathy.

Cardiac treatments in Duchenne patients

• Last Edited: 30 Aug 2009
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Dr. John Bourke explains the current thinking behind cardiac treatments for Duchenne and Becker patients, and explains the range of treatments that may be beneficialAlmost all Duchenne boys and yo...

Tags: Cardiac Treatments, heart treatment, cardiomyopathy, ACEinhibitors, captopril, enalapril, lisinopril, ramipril, perindopril, beta blockers, carvedilol, bisoprolol, metoprolol, steriod therapy, potassiumsparing diuretics, spironolactone, eplerenone, Dr John Bourke.

Duchenne/Becker muscular dystrophy in the family: have potential carriers been tested at a molecular level?

• Last Edited: 2 Mar 2011
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Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular disease. After identification of the mutation in the index patient, family members can be reliably investigated. Carrie...

Tags: cardiomyopathy, early diagnosis, carriers, heart priblems.