making muscle wasting history

Diagnosis of DMD

• Last Edited: 20 Jul 2009
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Once a child with DMD has been born in a family, it is often possible to offer prenatal diagnosis in future pregnancies, either for the mother or for other women who are found to be at risk of bei...

Tags: X chromosome, dystrophin gene, chorion villus biopsy.

Decipering a second genetic code- A review by Dr Karl Bettelheim

• Last Edited: 30 Jul 2010
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Article submitted by Dr Karl Bettelheim published on the 19 of May 2009 IntroductionOn the 6.5.2010, there appeared an important paper in Nature (1) and a commentary on it (2), ...

Tags: Dystrophin gene, current clinical trials on exonskipping.

The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy.

• Last Edited: 11 Mar 2011
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Duchenne muscular dystrophy (DMD) is associated with mutations in the dystrophin gene that disrupt the open reading frame whereas the milder Becker’s form is associated with mutations which ...

Tags: Exon Skipping, adenoassociated virus AAV, mRNA, dystrophin gene.