making muscle wasting history

Late Starters - A review by Dr Karl Bettelheim

• Last Edited: 30 Jul 2010
• Permanent link

Article submitted by Dr Karl Bettelheim published on the 3rd of June 2009Late StartersThere have been a number of papers recently, which are very relevant to potential DMD treatments and maybe eve...

Tags: dystrophin protein, amino acid coding, DMD mutations, AUG codons.

Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO

• Last Edited: 4 Feb 2011
• Permanent link

Splice modulation using antisense oligonucleotides (AOs) has been shown to yield targeted exon exclusion to restore the open reading frame and generate truncated but partially functional dystrophi...

Tags: peptidePMO, muscle, dystrophin protein.