making muscle wasting history

Genes

• Last Edited: 6 Apr 2009
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Genes are functional units of the genetic material in the chromosomes of each cell. This material is desoxyribonucleic acid, DNA. Its structure looks like an intertwined ladder, the double helix. ...

Tags: Gene, DNA, chromosome, cell, exon, RNA, Protein.

Dystrophin

• Last Edited: 12 Aug 2009
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What is Dystrophin?Dystrophin is a protein which binds to the muscle membrane cells and helps to maintain the muscle cell structure. It acts like a shock absorber for the muscle cells, and enable...

Tags: dystrophin, gene, protein, muscle, muscle cells, duchenne, muscular, dystrophy.

Exon skipping with U7 gene transfer

• Last Edited: 6 Jul 2009
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This is a gene therapy approach for Duchenne muscular dystrophy (DMD), based on the exon-skipping strategy and is currently under development. This approach consists of interacting with the splici...

Tags: gene, DNA, exon skipping, rna, U7, gene transfer.

Causes of duchenne muscular dystrophy

• Last Edited: 25 Aug 2009
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Duchenne muscular dystrophy may be caused due to a inherited genetic disorder. The dystrophin gene lives on a chromosome called the X chromosome (like houses on a street, chromosomes= street and G...

Tags: chromosome, gene, genetics, dystrophin, inheritance.

AAV1-FS344 injected into the quadriceps induced pronounced and durable increases in muscle size and strength in monkey.

• Last Edited: 13 Oct 2010
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Antagonists of myostatin, a blood-borne negative regulator of muscle growth produced in muscle cells, have shown considerable promise for enhancing muscle mass and strength in rodent studies and c...

Tags: follistatin, gene, muscle growth, muscle cells, muscle mass, strength.