making muscle wasting history

Inhibition of TGF-beta

• Last Edited: 14 Jul 2009
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The transforming growth factor beta (TGFβ) is a protein which inhibits the satellite cells (muscle stem cells) from regenerating muscle tissue. Mdx mice and also Duchenne boys have increa...

Tags: Duchenne Muscular Dystrophy, fibrosis, mdx mice, pirfenidone, TGF946.

Antioxidant Green tea extract decreases muscle necrosis in mdx mice and protects against reactive oxygen species.

• Last Edited: 13 Oct 2010
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Background: Duchenne muscular dystrophy is a severe X-linked congenital disorder characterized by lethal muscle wasting caused by the absence of the structural protein dystrophin. Objective: Becau...

Tags: Green tea, muscular dystrophy, reactive oxygen species, antioxidant, prevention, muscle necrosis, mdx mice, dystrophin, Xlinked congenital disease.