making muscle wasting history

Dosing regiment

• Last Edited: 28 May 2009
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this is potentially important ...Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice.http://www.ncbi.nlm.nih.gov/pubmed/194697091: Hu...

Tags: duchenne, dystrophin, dose, peptide, exon skipping, pmo, morpholino.

By-passing the nonsense mutation in the 4 CV mouse model of muscular dystrophy by induced exon skipping.

• Last Edited: 17 Sep 2010
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BackgroundDuchenne muscular dystrophy (DMD), a severe neuromuscular disorder, is caused by protein-truncating mutations in the dystrophin gene. Absence of functional dystrophin renders muscle fibr...

Tags: antisense oligomer, B6RosCgDmdmdx4CvJ 4CV mouse, Duchenne muscular dystrophy, exon skipping, morpholino.