Endpoints in clinical trials are used to determine an appropriate goal of a clinical trial, for example increased survival or decreased disease severity.

Biomarkers allow for the identification of disease, this could be a small molecule or gene produced as a result of a disease such as Duchenne. Biomarkers are used to determine clinical trial endpoints.

There are three types of biomarkers:

Diagnostic biomarkers (telling you something is wrong).

Prognostic biomarkers (predicting disease course and/or severity).

Therapeutic monitoring biomarkers (can predict whether a therapy will work or is working).